Cystatin SN inhibits auranofin-induced cell death by autophagic induction and ROS regulation via glutathione reductase activity in colorectal cancer
نویسندگان
چکیده
This corrects the article DOI: 10.1038/cddis.2017.100.
منابع مشابه
Auranofin induces apoptosis and necrosis in HeLa cells via oxidative stress and glutathione depletion.
Auranofin (Au), an inhibitor of thioredoxin reductase, is a known anti‑cancer drug. In the present study, the anti‑growth effect of Au on HeLa cervical cancer cells was examined in association with levels of reactive oxygen species (ROS) and glutathione (GSH). Au inhibited the growth of HeLa cells with an IC50 of ~2 µM at 24 h. This agent induced apoptosis and necrosis, accompanied by the cleav...
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عنوان ژورنال:
دوره 8 شماره
صفحات -
تاریخ انتشار 2017